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Manic depression is a disease that's little talked about and little understood. This programme presented by Stephen Fry explores the highs and the lows and the causes and the treatments of a condition that may affect as many as 2% of the population. Motivated by his own personal battle the programme follows Stephen Fry on an emotional but entertaining journey that takes him into the homes of stars such as Carrie Fisher Richard Dreyfuss and Rick Stein; into the lives of ordinary people who juggle this illness with their working lives; and into the surgeries of psychiatrists and the labs of researchers who are trying to help control the condition. In candid interviews we hear tales of mood swings and extremes of behaviour that can leave a sufferer living like Jekyll and Hyde; with reckless aggression crazy sex wild decisions and criminal impulses all thrown in. And we hear about the lows that make you wonder how they survive.

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